The BIOFIRE System and Your Immune System

The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare providers to choose the appropriate test first time. Patients benefit from quicker diagnosis and more targeted therapy. Clinicians benefit from a better stewardship of antibiotics. Labs are more efficient and can make cost savings.

The BioFire Pneumonia Plus Panel (PN panel) tests native sputum (including mini-BAL) as well as endotracheal sludge and bronchoalveolar slurries (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials in one hour.

Respiratory

The burning of biomass, including wood, plants and other organic materials, produces gaseous pollutants and fine particles that negatively affect the respiratory system. Furthermore, the environmental issues caused by forest fires, like droughts, may be amplified by climate change, thereby increasing the negative effects on human health.

In the United States, wildfire smoke has been linked to respiratory illnesses, including asthma, COPD and lung cancer. This type of pollution can also increase the risk of developing cardiovascular diseases and corner bioethanol bio fuel fireplace (site) is a major contributor to the burden of disease among the most vulnerable populations.

Wildfires have led to unhealthy levels of air pollution in many communities during the COVID-19 epidemic. The public health response has been limited to a public education campaign about the management of symptoms. This knowledge gap is concerning due to the evidence of possible health hazards from the continued exposure to smoke and other sources of poor air quality.

Researchers are currently assessing the best ways to protect public's health during future incidents of this type. NIH invests in research on this crucial public health issue through the BLUE CORAL and FIRE CORAL studies.

For the first time an prospective cohort study will examine long-term effects resulting from exposure to smoke from wildfires as well as other sources. FIRE CORAL is a study that seeks adult participants who are hospitalized for COVID-19 index episodes and who speak English or Spanish however, they are not pregnant. The protocol for Fire Coral includes a series of in-person assessments that objectively measure pulmonary function testing, lung imaging and functional assessment.

The lungs are the most sensitive to the effects of smoke and other particles because they can trigger or worsen chronic respiratory diseases like emphysema or COPD, and increase the risk of developing pneumonia. A variety of steps can be taken to avoid or lessen the negative health effects resulting from exposures to smoke, such as avoidance of outdoor activities whenever possible and using the EPA's "N95" mask designed to catch fine particles.

Smoke can also cause irritation of the throat and eyes and can cause an irritated nose. To reduce the symptoms the lungs must be flushed with plenty of water and taking medications that decrease inflammation, like corticosteroids.

Bloodstream

Your bloodstream is at the forefront of fighting germs that invade your body. Special cells called dendritic cells are like your fire department's call center. they gather antigens (molecules that trigger an immune response) from germs that are invading your body and release proteins that alert other white blood cells to come to fight them. Circulating total white blood cells, differentials, and band cells were boosted during firefighters' firefighting shifts, as compared to levels following physical exertion with no firefighting.

Skin

As the wildfires in California produced smoke and smoke into the air this past winter and fall, dermatologists were concerned about how that might affect the skin of people exposed to it. Maria Wei is a graduate student from University of California, Irvine. She investigates how the extreme pollution from wildfires affects the skin. Her research was published in Scientific Reports on April 22.

Wei's study shows that the temperature of the skin changes according to the length of time the body has been exposed. It can take as long as two hours for the skin to reach its flash point--the point at which it burns and turns into a ashy. It's crucial not to be near a campfire or fire, and you should always wear protective clothing if you're out in a humid or hot day.

Forest fires will continue occur, despite the measures taken to stop wildfire pollution. Wei is predicting that the number of people suffering the consequences of wildfires will increase as climate change causes more forests to be burned. That means more people will need to wear long sleeves, hats, and thick moisturizers.

It's also worth knowing that atopic dermatitis (itchy skin) that many people suffer from is often exacerbated by wildfire air pollution. The reason for this is due to the particles in smoke can clog pores, making the condition worse.

Atopic dermatitis may make people more sensitive towards UV light. This can be made worse by smoke from wildfires. This makes people more likely to visit tanning salons, and it may cause the skin to get darker with less protection than they need to.

While a ice and fire facial may help reduce the effects of atopic dermatitis it's not recommended for anyone with an open wound or a rash on their face. This treatment is not recommended for people with active acne or if you are pregnant or nursing. The IS Clinical Fire & Ice Facial is offered at Novuskin Las Vegas' premier membership MedSpa is a result-driven, intensive facial that bridges the mild facelift and the peel, without requiring time off. It is designed to resurface skin, improve rosacea and reduce the appearance of acne scars and fine lines, as well as encourage cellular regeneration. It's an incredible treatment to give yourself a radiant glow.

Infections

The human body is comprised of a complex system of organs and tissues which work together to protect us against infection. Infections are caused by microscopic organisms such as bacteria, viruses, parasites and fungus that infiltrate healthy cells and cause them to replicate beyond control. Your immune system could react by exhibiting symptoms of illness. The symptoms could range from a stuffy or runny nose to stomach ache and can include a fever that is high, swollen glands, and a rash. The nature of the infection and its location can affect the severity of your symptoms.

Infections spread in many ways however the most common are transmitted from person to person by droppings that hang in the air after coughing or sneezing. This is how bacterial diseases such as tuberculosis, strep and meningococcal disease and viral infections such a common cold and influenza, are spread. Certain bacterial infections like skin infections or sexually transmitted diseases (STIs) like Chlamydia and gonorrhea can be transmitted through direct contact with affected mucous or tissue surfaces, or indirectly by contaminated surfaces. Certain infections caused by bacteria are transmitted by insects like ticks, fleas or mosquitoes.

The virus and the parasites are small enough to get into your bloodstream and infect your cells which leads to serious illnesses like the common cold or AIDS. Fungi are responsible for a myriad of skin conditions such as ringworm and athlete's foot. Other types infect the lungs or nervous system, like the rabies virus.

The BioFire PN Panel employs our innovative FilmArray technology to analyze a complete list of pathogens responsible for upper respiratory infections in sputum or bronchoalveolar lavage fluid samples. The kit includes a reagent bag that contains all the chemistry necessary to perform reverse transcription, nested multiplex PCR and detection with a single machine. This is a simple method that assists clinicians identify and treat patients who have a variety respiratory symptoms. This test has received an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.