The BIOFIRE System and Your Immune System

The BIOFIRE System provides syndromic infectious disease testing, which allows healthcare providers to select the most appropriate test, the first time. Patients benefit from faster diagnoses and more targeted treatments. Clinicians benefit from a better stewardship of antibiotics. Labs improve efficiency and cost savings.

The BioFire FilmArray Pneumonia plus panel (PN panel) examines native sputum, endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 clinically relevant pathogens and antimicrobial resistance genes. The panel provides semiquantitative results within an hour.

Respiratory

The burning of biomass, including plants, wood and other organic materials, creates gaseous pollution and fine particulates that negatively affect the respiratory system. Moreover, the environmental problems caused by forest bio Ethanol fires uk, like droughts, could be potentiated by climate change, thereby increasing the negative effects on the human health.

In the United States wildfire smoke is associated with hospitalizations for respiratory diseases such as asthma, COPD, and lung cancer. Additionally, this kind of air pollution can be an underlying risk factor for cardiovascular diseases and is a significant contributing factor to the burden of disease in the most vulnerable populations that include those with lower socioeconomic status (SES).

The wildfires have caused unhealthy levels of air pollutants in several communities during the COVID-19 epidemic. However, the public health response to this environmental issue is sporadic and mainly focused on educating people about symptom management. This knowledge gap is alarming due to the fact that smoking cigarettes and other sources of air pollution can cause health problems.

Researchers are now looking at the best ways to safeguard public health in future events similar to this. NIH is funding research on this important public health issue through the BLUE CORAL study as well as its successor FIRE CORAL.

For the first time the study is a prospective cohort study that will examine long-term effects resulting from exposure to smoke from wildfires as well as other sources. FIRE CORAL enrolls adults who are hospitalized for COVID-19 index episodes and who speak English or Spanish however, they are not pregnant. The Fire Coral protocol includes a variety of assessments in person that objectively measure pulmonary function testing and lung imaging, as well as functional assessment.

Smoke and other particles can trigger or worsen chronic respiratory conditions like emphysema COPD and pneumonia. A number of steps can be taken to prevent or lessen the negative health effects resulting from exposures to smoke, which includes avoidance of outdoor activities whenever feasible and wearing the EPA's "N95" mask, which is designed to capture fine particles.

Smoking cigarettes can cause irritation to the throat, eyes and nose. To reduce the symptoms the lungs must be flushed by drinking plenty of water and taking medicines which reduce inflammation, like corticosteroids.

Bloodstream

Your bloodstream is at the forefront of fighting off germs that enter your body. Dendritic cells, specific cells, serve as the call center for your fire department. They gather antigens from bacteria and release proteins to signal other white cells to fight. Circulating white blood cell counts, differentials and band cells were boosted following firefighters' bio-ethanol fire-fighting shifts, as compared to levels following strenuous physical exercise with no firefighting.

Skin

Dermatologists were concerned that smoke and ash that resulted from the California wildfires could have negative effects on the skin of those who were exposed to the smoke and ash. Maria Wei, a graduate student at University of California, Irvine, is studying how extreme pollution from wildfires affects the skin. Her research was published on April 22 2012 in Scientific Reports.

Wei's research shows that the temperature of a person's skin changes depending on the length of time that the body is exposed to flames. It can take up to two hours for the skin of a person to reach its "flash point"--the moment at which it starts to burn and then turns to ash. It's crucial not to be near a campfire or fire and wear protective clothing if you're out on a hot or humid day.

While it's important to be vigilant against fire-related pollution, there's no way to stop forest bioethanol fuel fires from happening. Wei believes that as climate change causes forests to burn more, the number of people suffering from wildfires will increase. That means more people will be required to wear long sleeves, hats, and thick moisturizers.

Air pollution from wildfires can cause atopic dermatitis to the skin, which causes itchy skin in many people. She suggests that this is because the particles in smoke can clog pores, thereby making atopic dermatitis worse.

Another issue is that atopic dermatitis is known to make people more sensitive to UV light, which can be aggravated by wildfire smoke. This can result in people seeking out tanning salons and get tanned with less protection.

While a cold and fire facial can help lessen the effects of atopic skin dermatitis, it's not recommended for anyone who has an open wound or a rash on their face. This treatment is not recommended for patients with active acne, or if you are pregnant or nursing. The IS Clinical Fire & Ice Facial, at Novuskin Las Vegas' premier membership MedSpa is a result-driven, intensive facial that bridges between an easy facelift and a peel, without requiring downtime. It is designed to resurface skin, reduce rosacea, decrease acne scarring and fine lines, as well as encourage cellular regeneration. This is a great treatment to give your skin a radiant glow.

Infections

The human body is a complicated network of organs and tissues that work to shield us from infections. Infections can be caused by microorganisms such as parasites, viruses and bacteria which infect healthy cells, causing them to multiply uncontrollably. Your immune system can react by exhibiting symptoms of illness. These symptoms can include anything from a runny or stuffy nose to stomach ache however, they may also include a high fever swelling of the glands, an skin rash. The severity of your symptoms may be affected by the nature of the disease, its location, and even your temperature.

Infections can be spread in a variety of ways, but they are most often spread via droplets of air that remain after a sniff or cough. Bacterial infections like tuberculosis and strep throat meningococcal disease, and Legionnaires disease spread through this method, along with certain viral infections such as the common cold and influenza. Some bacterial infections such as skin infections or sexually transmitted diseases (STIs) like gonorrhea or chlamydia are spread by direct contact with infected tissues or mucous surfaces or indirectly through contaminated surfaces. Certain bacterial infections are transmitted by insects, such as ticks, fleas, or mosquitoes.

Viruses and some parasites are small enough to get into your bloodstream and infect your cells which can lead to serious diseases such as the common cold and AIDS. Fungi are responsible for a myriad of skin conditions such as ringworm and athlete's foot. Other types affect the lungs or the nervous system, such as the rabies virus.

The BioFire PN Panel utilizes our innovative FilmArray technology to test for a complete list of pathogens responsible for upper respiratory infections in sputum and the bronchoalveolar lavage samples. The kit includes the reagent pouch which stores all the necessary chemicals to perform reverse transcription PCR, nested analysis and detection using a single machine. This is a simple solution that assists clinicians identify and treat patients suffering from several respiratory symptoms. The test has been approved as an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high complexity labs.