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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are often described as a focus on the practical aspects of designing a study that include recruitment and consent, adherence and the use of routinely available equipment.

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A practical trial that employs different investigators and participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is required for practical trials to be valid, and 프라그마틱 정품확인 it also helps to reduce the chance of bias in the results. A high degree of heterogeneity, however can result in problems with the trial design.

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The aim of pragmatic trials is to simulate real-life situations and achieve maximum validity externally. They are usually requested by practitioners and policy makers to aid in their decision-making. They can also be used to assess the cause-effect relationship of an intervention and its results. However, they should not be used to substitute for 프라그마틱, Lovewiki official website, explanatory studies.

The pragmatism idea is controversial and there are doubts about whether pragmatic trials should replace explanatory tests or if they are an addition to them. Schwartz and Lellouch1 suggested the distinction between explanation studies, which support a physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform the practice and policy decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the characteristics of a practical study that includes recruitment, design, delivery of the intervention and its follow-up.

There is a positive increase in the number pragmatic trials published. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs) resulted in 34 articles, as shown in red in Figure 2. This is a sign that the health science community is becoming more sensitive to the subject of pragmatism. However, it is important to note that the majority of these studies were conducted in primary care settings.