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Memory Consolidation Throughout REM Sleep

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작성자 Niki 작성일25-09-09 12:25 조회2회 댓글0건

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The presence of dreaming throughout speedy-eye-motion (REM) sleep indicates that memory formation could occur throughout this sleep stage. However now, researchers from Japan have found that exercise in a selected group of neurons is important for memory consolidation during REM sleep. In a examine revealed this month in Neuron, researchers from College of Tsukuba and the College of Tokyo have revealed that grownup-born neurons (ABNs) in the hippocampus, which is a mind area associated with memory, are liable for memory consolidation during REM sleep. Neurogenesis, the method by which new neurons are formed, takes place in the hippocampus throughout the lifespan of animals, including people. At present, little is understood in regards to the contribution of ABNs to memory formation during sleep, one thing the researchers at University of Tsukuba and the College of Tokyo aimed to deal with. Associate Professor Masanori Sakaguchi. To do this, the researchers exposed mice to a context-specific fear memory task. Then, they recorded activity in specific ABNs across the learning, consolidation, and retrieval stages of memory.



Professor Masashi Yanagisawa, the other senior writer of the examine. Their information symbolize causal evidence that exercise in young ABNs during REM sleep is necessary for memory consolidation. This is a vital improvement as the exercise and function of ABNs in memory consolidation throughout sleep was beforehand unknown, as was the kind of hippocampal neuron answerable for memory consolidation during sleep. Clarification of these possibilities may lead to a deeper understanding of how memories are formed, retrieved, and consolidated, and will facilitate the event of new treatments for memory disorders. Supplies supplied by University of Tsukuba. Observe: Content material may be edited for model and length. 1. Deependra Kumar, Iyo Koyanagi, Alvaro Provider-Ruiz, Pablo Vergara, Sakthivel Srinivasan, Yuki Sugaya, Masatoshi Kasuya, Tzong-Shiue Yu, Kaspar E. Vogt, Masafumi Muratani, Takaaki Ohnishi, Sima Singh, Catia M. Teixeira, Yoan Chérasse, Toshie Naoi, Szu-Han Wang, Pimpimon Nondhalee, Boran A.H. Osman, Naoko Kaneko, Kazunobu Sawamoto, Steven G. Kernie, Takeshi Sakurai, Thomas J. McHugh, MemoryWave Community Masanobu Kano, Masashi Yanagisawa, Masanori Sakaguchi. Sparse Activity of Hippocampal Grownup-Born Neurons during REM Sleep Is necessary for Memory Consolidation.



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