The BIOFIRE System and Your Immune System

The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare providers to select the right test first time. Patients benefit from quicker diagnosis and more specific treatment. Clinicians benefit from better antibiotic stewardship. Labs gain efficiency and cost savings.

The BioFire FilmArray Pneumonia plus panel (PN panel) analyzes native sputum endotracheal aspirate, and bronchoalveolar specimens (including mini-BAL) for 33 pathogens that are clinically relevant and antimicrobial resistance genes, with semiquantitative results that take less than an hour.

Respiratory

The burning of biomass (wood plants, agro-forestry and other organic material) produces gaseous pollutants as well as fine particulate matter which negatively impact the respiratory system. Climate change may increase the negative effects of forest fires to human health.

In the United States wildfire smoke is associated with hospitalizations for respiratory diseases like asthma, COPD, and lung cancer. Furthermore, this type of air pollution can be an important risk factor for cardiovascular disease and a significant contributing factor to the burden of disease for the most vulnerable population that include those who are of lower socioeconomic status (SES).

During the COVID-19 epidemic, many communities were exposed to unhealthy levels of air pollution resulting from wildfires. The public health response has been limited to a public education campaign regarding managing symptoms. This lack of knowledge is troubling due to the evidence of possible health hazards from the continued exposure to smoke and other sources of poor air quality.

Researchers are currently evaluating the best ways to safeguard public health during future events of this kind. NIH invests in research on this critical public health issue through the BLUE CORAL and FIRE CORAL studies.

For the first time, a prospective study will evaluate long-term outcomes of exposure to smoke from wildfires and other sources. FIRE CORAL recruits adult participants who are hospitalized for COVID-19 index episode and speak English or Spanish but aren't pregnant. The Fire Coral protocol includes a series of in-person assessments that objectively measure the pulmonary function testing lung imaging and functional assessment.

Smoke and other particles can trigger or worsen respiratory conditions like emphysema COPD, and pneumonia. Smoke exposure can have negative effects on your health. To lessen or stop these effects, you should avoid outdoor activities and wear the EPA "N95" mask. The mask is designed to capture fine particles.

Smoking cigarettes can cause irritation to the eyes and throat, and can cause the nose to run. To minimize symptoms, drink lots of water and take medications that reduce inflammation, such corticosteroids.

Bloodstream

Bloodstream is the first line of defense against germs that enter your system. Dendritic cells are special cells, act as the call center for your fire department. They gather antigens from germs and release proteins that alert other white cells to fight off them. The total white blood cells, differentials, and ethanol fire Table (www.designlight.co.kr) band cells increased after firefighters' firefighting tasks in comparison to levels after intense exercise without firefighting.

Skin

Dermatologists were concerned that smoke and ash of the California wildfires could cause negative effects on the skin of those who were exposed to the smoke and ash. Maria Wei is a graduate student from University of California, Irvine. She examines how extreme wildfire pollution affects the skin. Her research was published in Scientific Reports on April 22nd.

The study of Wei shows that the temperature of the skin fluctuates dependent on the amount of time the body is exposed. It can take as long as two hours for the skin of someone to reach their "flash point"--the point where it begins to burn and then turn into ash. It's crucial not to be near a fire pit or campfire and wear protective clothing if going outside in a humid or hot day.

Forest fires will continue occur, despite the steps taken to stop fires from causing pollution. Wei believes that as the climate changes cause forests to burn more quickly, the number of people who suffer from wildfires will increase. This means that more people will have to wear hats and long sleeves as well as thick moisturizers.

It's also worth knowing that atopic dermis (itchy skin) that a lot of people suffer from is often exacerbated by air pollution from wildfires. The particles in smoke can clog pores which can cause skin irritation.

Another issue is that atopic dermatitis tends to make people more sensitive to UV light, which can also be aggravated by smoke from wildfires. This can result in people seeking out tanning salons to apply a tan with less protection.

A fire and ice treatment can help reduce atopic skin dermatitis symptoms, but it is not recommended for those with an open wound or rash. This treatment is not recommended for patients with active acne or if you are pregnant or nursing. The IS Clinical Fire & Ice Facial, at Novuskin Las Vegas' premier membership MedSpa is a results-driven intensive facial that bridges the mild facelift and the peel, without requiring time off. It's designed to rejuvenate the skin, improve the appearance of rosacea, reduce acne scarring, diminish wrinkles, and promote cell renewal. This is a great way to provide your skin with a radiant glow.

Infections

The human body is made up of a complex set of organs and tissue which work together to protect us against infections. Infections are caused by microscopic organisms such as parasites, viruses, bacteria and fungi that infect healthy cells and cause them to multiply beyond control. Your immune system may react by displaying symptoms of illness. These symptoms could range from a swollen or achy nose to stomach ache however, they may also include a fever that is high, swollen glands, and a eruption. The type of infection and the location can impact the symptoms.

Infections can spread in various ways, but the most common is through airborne droplets that remain after a sniff or cough. This is how bacterial infections like strep, tuberculosis and meningococcal disease and viral infections, such as the common cold and influenza are transmitted. Certain bacterial infections, such as skin infections and sexually transmitted diseases (STIs) like gonorrhea and Chlamydia, can be transmitted through direct contact with infected tissue or mucous membranes or by indirect contact with contaminated surfaces. Certain bacterial diseases are carried by bugs like ticks, mosquitoes or fleas, and are spread when these bugs bite you.

Viruses and some parasites are small enough to penetrate your bloodstream and infect your cells, which can cause serious illness such as the common cold and AIDS. Fungi can cause skin conditions like athlete's feet and ringworm, while others infect the respiratory tract and nervous system.

The BioFire Panel uses our innovative FilmArray technology to analyze the sputum and bronchoalveolar fluid samples to determine a comprehensive list of pathogens involved in upper respiratory infection. The kit includes the reagent pouch which stores all the necessary chemistry to perform reverse transcription PCR, nested multiplex analysis and detection on a single machine. It's a simple-to-use tool to assist clinicians in identifying syndromic patterns and treat patients with various respiratory symptoms. This test has received an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.